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17 Jul 2018 22:36

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Adverse effects include destruction of natural erectile tissue, risk of infection. Of note, pelvic lymph node dissection was not associated with an increased risk of postoperative ED. 27 Only patient age at surgery, preoperative erectile function, and pathologic tumor stage predicted erectile function recovery. A severed nerve can lead to weakened erections or the inability to achieve an erection, whereas interruption to normal blood supply can affect the ability to maintain an erection.

Men with cancer in the pelvis are more likely than are men with other cancers to have ED after treatment, given the location of the neurovascular pathways responsible for erections. 10 In addition, increased age (> 60 years) diminished pretreatment erectile function, and combination therapy with EBRT and/or ADT significantly increases ED after brachytherapy. Rivin del Campo et al 15 conducted a review of the literature to examine whether there was a relationship between the radiation dose to the penile bulb and risk of ED in men treated for prostate cancer with external-beam radiation therapy (EBRT).

Adverse effects of cisplatin in combination with vinblastine and bleomycin treatment include nephrotoxicity, myelosuppression, pulmonary toxicity, therapy-related secondary malignancies, vascular toxicity, neurotoxicity, and infertility. Recovery of erectile function is possible after discontinuation of short-term ADT (eg, in men who receive neoadjuvant and adjuvant ADT with radiation therapy for high-risk localized or locally advanced prostate cancer). 3 The nerves travel along the prostate and enter the corpora cavernosa and corpus spongiosum to regulate blood flow during erection and detumescence.

NORMAL ANATOMY AND PHYSIOLOGY OF PENILE ERECTIONS. Table 1. Cancer Treatment Effects on Sexual Dysfunction in Men. In addition, depressed feelings about having cancer can affect sexuality, causing a range of signs and symptoms that can lead to ED. Chemotherapy, hormone therapy, surgery, and radiation can all cause sexual adverse effects.


Understanding and Managing Erectile Dysfunction in Patients Treated for Cancer. Erectile Dysfunction is primarily physical in origin, but psychological factors, alone or in combination with physical factors, can cause ED. Among the conditions associated with ED are: Erectile Dysfunction (ED) is a significant and common medical condition.

Peyronie's disease is a medical condition characterized by the development of a lump on the shaft of the penis. The effect of Fildena citrate (Fildena) on the relationship between changes in systemic blood pressure and coronary blood flow. Research indicates that as many as 75 percent of all ED cases result from medical problems, usually related to the vascular (blood supply) system in the penis.

This is why men who experience ED should go to the doctor to get checked for heart disease. Getting an erection is a process that includes physical, hormonal, and psychological elements. Erectile dysfunction (ED) is a common male sexual disorder.

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